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1.
Journal for ReAttach Therapy and Developmental Diversities ; 6(3s):59-69, 2023.
Article in English | Scopus | ID: covidwho-20231968

ABSTRACT

Whether or not listening skills can be used to measure grammatical ability has been a hot topic of controversy in the language learning community. However, existing study results aren't satisfactory in and of themselves. As a result, considering the current research gap, this study was carried out to solve the issue. To begin, the researchers used a mean listening score to assess the listening skills of 50 ESL first-year students at a public institution. Second, frequency and sentence analysis were used to identify the students' most frequent mistakes and difficulty in listening for grammatical differences. When hearing comprehension outcomes were being evaluated, a written composition activity was used to verify them. There was a strong correlation between the degree of skill of the respondents in listening for grammatical differences between the single and plural forms of subjects and predicates, as well as in the ability to distinguish between the present and past tense verbs. However, more complicated syntactic formulations were discovered to have specific issues. According to the results, the listeners get disoriented and disturbed when the test sentence contains intermediate words, phrases, or subordinate sentences. These difficulties in remembering what they learned at school may result from socio-psychological issues—the intervening words impaired their ability to concentrate and recall information when they were not in a classroom. As a result of the COVID 19 epidemic, instructors and students alike have been compelled to adapt to a new learning environment: the virtual classroom. Online testing and results processing was done under this, considering that electronic platforms are a moderating factor. EFL and ESL specialists like (Shao et al., 2019) and (Walsh & Rsquez 2020) have recognized that this alteration in the modality of teaching influences methods of learning that have not necessarily been delineated previously. While not the primary focus of the research, this work still underlines the new socio-technological component as an essential mediator of listening evaluation for greater grammatical competence © 2023, Journal for ReAttach Therapy and Developmental Diversities.All Rights Reserved.

2.
Environ Res ; 229: 115892, 2023 07 15.
Article in English | MEDLINE | ID: covidwho-2296404

ABSTRACT

The COVID-19 pandemic has brought increments in market sales and prescription of medicines commonly used to treat mental health disorders, such as depression, anxiety, stress, and related problems. The increasing use of these drugs, named psychiatric drugs, has led to their persistence in aquatic systems (bioaccumulation), since they are recalcitrant to conventional physical and chemical treatments typically used in wastewater treatment plants. An emerging environmental concern caused by the bioaccumulation of psychiatric drugs has been attributed to the potential ecological and toxicological risk that these medicines might have over human health, animals, and plants. Thus, by the application of biocatalysis-assisted techniques, it is possible to efficiently remove psychiatric drugs from water. Biocatalysis, is a widely employed and highly efficient process implemented in the biotransformation of a wide range of contaminants, since it has important differences in terms of catalytic behavior, compared to common treatment techniques, including photodegradation, Fenton, and thermal treatments, among others. Moreover, it is noticed the importance to monitor transformation products of degradation and biodegradation, since according to the applied removal technique, different toxic transformation products have been reported to appear after the application of physical and chemical procedures. In addition, this work deals with the discussion of differences existing between high- and low-income countries, according to their environmental regulations regarding waste management policies, especially waste of the drug industry.


Subject(s)
COVID-19 , Water Pollutants, Chemical , Animals , Humans , Biocatalysis , Bioaccumulation , Pandemics , Water , Water Pollutants, Chemical/analysis , Biodegradation, Environmental
3.
Indonesian Journal of Electrical Engineering and Computer Science ; 30(2):1120-1127, 2023.
Article in English | Scopus | ID: covidwho-2289220

ABSTRACT

The coronavirus pandemic has affected not only health but also the economy. The use of big data in finding information can be used to gain profits that logistics companies can utilize to survive during the pandemic. This study conducted text-mining research on service consultant sites in the logistics sector. This study aims to present frequency diagrams, analyze sentiment using the National Research Council (NRC) lexicon, present bigrams, and seek knowledge about strategies to minimize shipping costs and maintain inventories of manufactured goods. The words "supply", "chain", and "COVID-19" are words that are used frequently throughout the article. The results of this study showed that the words that often appear from word excavation are the words "supply", "chain", "logistics", "kpis," and "inventory". Then emotion trust becomes an emotional word that often appears in articles. The words "Supply" and "pandemic" are the words that seem the most positive and negative words, respectively. The words "COVID-19", "safety stock", and "inventory management" are words that often appear together. The result of discovery knowledge is that logistics consultants offer emotions of trust and provide many insights on minimizing shipping costs and maintaining inventory during a pandemic. © 2023 Institute of Advanced Engineering and Science. All rights reserved.

4.
Sustainability ; 15(1):283, 2023.
Article in English | MDPI | ID: covidwho-2166854

ABSTRACT

The COVID-19 pandemic has inflicted structural shocks on the global economic system by raising high economic uncertainty. Policymakers are exploring alternative measures and incentivizing foreign direct investment for the restoration of global economic operations to achieve short- and long-term growth. Given this, the study examines the global response of FDI inflow to measure the change in productive capacity. The productive capacity is proxied by structural change, private business sector, institutional quality, transportation infrastructure development, and natural capital. The study implements empirical analysis for a large panel of 170 countries in a data set from 2000 to 2021. Furthermore, the study employed the cross-sectional augmented auto-regressive distributed lag (CS-ARDL) econometric estimation method for better examinations of current changes in an economic outbreak. From the results of the study, the estimations reveal that FDI inward has significant positive impact over the private business sector, institutional quality, transportation infrastructure, and natural capital on inward FDI. In accordance with discussions, the study suggests several pragmatic policy implications to achieve maximum output by utilizing the inward FDI as incentivized by the governments of the selected countries.

5.
Quality of Life in Asia ; 14:203-219, 2022.
Article in English | Scopus | ID: covidwho-2014041

ABSTRACT

Tui-na, a form of Chinese Medicine treatment for orthopaedics-related problems has been widely known for its efficacy. It is also a form of treatment that requires close physical interaction between the Chinese Medicine practitioner and the patient. However, due to COVID-19 pandemic, social distancing measures were imposed, limiting closed physical interaction. In Hong Kong Baptist University where Chinese Medicine course on Tui-na was offered, the COVID-19 social distancing measures affected the students service-learning activities and were unable to offer Tui-na interventions to elderlies who may benefit from it. As a result of these restrictions, the course instructors decided to pilot an online service-learning to deliver Tui-na intervention to 6 elderlies. The aim of the current study was to examine the impact of Tui-na online service-learning from the perspective of service-recipients and service-partner. Qualitative data were collected through phone interviews and were analysed using Thematic. The results of the qualitative interviews first suggested that the participants were generally satisfied with the service received. Second, key areas that could have further implications on the success of conducting Tui-na e-service-learning were identified. These include communication, logistic and technology. The implication of these findings and its limitations and lessons learned would be beneficial towards future online skill-based courses. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

6.
Environ Sci Pollut Res Int ; 29(46): 69117-69136, 2022 Oct.
Article in English | MEDLINE | ID: covidwho-1982294

ABSTRACT

The coronavirus pandemic of 2019 has already exerted an enormous impact. For over a year, the worldwide pandemic has ravaged the whole globe, with approximately 250 million verified human infection cases and a mortality rate surpassing 4 million. While the genetic makeup of the related pathogen (SARS-CoV-2) was identified, many unknown facets remain a mystery, comprising the virus's origin and evolutionary trend. There were many rumors that SARS-CoV-2 was human-borne and its evolution was predicted many years ago, but scientific investigation proved them wrong and concluded that bats might be the origin of SARS-CoV-2 and pangolins act as intermediary species to transmit the virus from bats to humans. Airborne droplets were found to be the leading cause of human-to-human transmission of this virus, but later studies showed that contaminated surfaces and other environmental factors are also involved in its transmission. The evolution of different SARS-CoV-2 variants worsens the condition and has become a challenge to overcome this pandemic. The emergence of COVID-19 is still a mystery, and scientists are unable to explain the exact origin of SARS-CoV-2. This review sheds light on the possible origin of SARS-CoV-2, its transmission, and the key factors that worsen the situation.


Subject(s)
COVID-19 , Chiroptera , Animals , COVID-19/epidemiology , Humans , Mutation , SARS-CoV-2
7.
Humanit Soc Sci Commun ; 9(1): 242, 2022.
Article in English | MEDLINE | ID: covidwho-1937495

ABSTRACT

This paper investigates the role of environmental, social, and governance (ESG) performance in stock prices during the market financial crisis caused by the COVID-19 pandemic. We use the Chinese listed company data as the bases for adopting an event-study method to identify the impact of ESG performance on cumulative abnormal returns. Empirical results suggest that ESG performance significantly increases firms' cumulative abnormal returns and has asymmetric effects during the pandemic. Our results are robust to various robustness checks that consider the replacement of event window period, ESG measurement, adding other control variables, and sample exclusion of Hubei Province. We further find that reputation and insurance effects are important mechanisms through which ESG performance influences stock prices. Lastly, heterogeneous analyses show that ESG effects are considerably pronounced among firms with low human capital and bad image and in high-impact regions.

8.
Water ; 14(12):1842, 2022.
Article in English | MDPI | ID: covidwho-1884452

ABSTRACT

The COVID-19 pandemic has challenged healthcare systems worldwide. Efforts in low-to-middle-income countries (LMICs) cannot keep stride with infection rates, especially during peaks. A strong international collaboration between Arizona State University (ASU), Tec de Monterrey (TEC), and Servicios de Agua y Drenaje de Monterrey (Local Water Utilities) is acting to integrate wastewater-based epidemiology (WBE) of SARS-CoV-2 in the region as a complementary approach to aid the healthcare system. Wastewater was collected from four sewer catchments in the Monterrey Metropolitan area in Mexico (pop. 4,643,232) from mid-April 2020 to February 2021 (44 weeks, n = 644). Raw wastewater was filtered and filter-concentrated, the RNA was extracted using columns, and the Charité/Berlin protocol was used for the RT-qPCR. The viral loads obtained between the first (June 2020) and second waves (February 2021) of the pandemic were similar;in contrast, the clinical cases were fewer during the first wave, indicating poor coverage. During the second wave of the pandemic, the SARS-CoV-2 quantification in wastewater increased 14 days earlier than the COVID-19 clinical cases reported. This is the first long-term WBE study in Mexico and demonstrates its value in pandemic management.

9.
International Journal of Islamic and Middle Eastern Finance and Management ; 15(2):406-424, 2022.
Article in English | ProQuest Central | ID: covidwho-1794905

ABSTRACT

Purpose>This study aims to investigate the relationship between capital regulation and risk-taking behavior (financial stability) concerning the impacts of the recent global (COVID-19) crisis and diverse ownership structure.Design/methodology/approach>The analysis uses an unbalanced panel data set from 32 commercial banks of Bangladesh for 2000–2020. The authors use the two-step system generalized method of moments and three-stage least squares to produce the study outcomes.Findings>The robust results reveal that the relationship between capital regulation and risk (financial stability) is negative (positive) and bi-directional. More significantly, COVID-19 makes banks fragile and demands more capital to absorb risk. However, the effect of COVID-19 is heterogeneous when the authors consider ownership structure. Among the diverse ownership styles, Islamic and active shareholding show their controlling wheel on capital regulation and risk-taking aptitude (financial stability) during the global (COVID-19) crisis. In normal economic conditions, private banks and minority active shareholding can be a good determinant for capital regulation and risk (financial stability). On the other hand, state-owned and large banks have been found as less capitalized and highly risky.Originality/value>This study is the pioneer in exploring capital regulation and risk toward the recent global (COVID-19) crisis.

10.
Polymers (Basel) ; 14(6)2022 Mar 17.
Article in English | MEDLINE | ID: covidwho-1765816

ABSTRACT

Plastics have become an essential part of the modern world thanks to their appealing physical and chemical properties as well as their low production cost. The most common type of polymers used for plastic account for 90% of the total production and are made from petroleum-based nonrenewable resources. Concerns over the sustainability of the current production model and the environmental implications of traditional plastics have fueled the demand for greener formulations and alternatives. In the last decade, new plastics manufactured from renewable sources and biological processes have emerged from research and have been established as a commercially viable solution with less adverse effects. Nevertheless, economic and legislative challenges for biobased plastics hinder their widespread implementation. This review summarizes the history of plastics over the last century, including the most relevant bioplastics and production methods, the environmental impact and mitigation of the adverse effects of conventional and emerging plastics, and the regulatory landscape that renewable and recyclable bioplastics face to reach a sustainable future.

11.
Biosensors (Basel) ; 12(3)2022 Mar 17.
Article in English | MEDLINE | ID: covidwho-1753435

ABSTRACT

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the ongoing COVID-19 (coronavirus disease-2019) outbreak and has unprecedentedly impacted the public health and economic sector. The pandemic has forced researchers to focus on the accurate and early detection of SARS-CoV-2, developing novel diagnostic tests. Among these, microfluidic-based tests stand out for their multiple benefits, such as their portability, low cost, and minimal reagents used. This review discusses the different microfluidic platforms applied in detecting SARS-CoV-2 and seroprevalence, classified into three sections according to the molecules to be detected, i.e., (1) nucleic acid, (2) antigens, and (3) anti-SARS-CoV-2 antibodies. Moreover, commercially available alternatives based on microfluidic platforms are described. Timely and accurate results allow healthcare professionals to perform efficient treatments and make appropriate decisions for infection control; therefore, novel developments that integrate microfluidic technology may provide solutions in the form of massive diagnostics to control the spread of infectious diseases.


Subject(s)
Biosensing Techniques/methods , COVID-19/diagnosis , Microfluidics , SARS-CoV-2/isolation & purification , Antibodies, Viral/blood , COVID-19/epidemiology , Humans , Point-of-Care Systems , Point-of-Care Testing , SARS-CoV-2/immunology , Seroepidemiologic Studies
12.
Journal of Pure & Applied Microbiology ; 16(1):1-2, 2022.
Article in English | Academic Search Complete | ID: covidwho-1732584

ABSTRACT

The recent emergence of the novel Omicron SARS-CoV-2 Variant, first detected in Gauteng Province of South Africa in mid- November 2021, has become a global concern. Several countries witnessed rapid transmission of omicron in the past months. This variant can increase the rate of virus transmission, risk of reinfection and enable omicron to continue its spread in the community. There is no evidence that COVID-19 can spread through food, and people can catch up with this virus through food materials. This virus can not survive and multiple on the surfaces of food packaging. The main routes of this virus transmission and spread may be during close contact and directly from an infected person to a healthy person. Touching a contaminated surface and objects such as doorknobs, table surfaces, everyday use equipment, touching screens and shaking hands and then touching the mouth, nose, or eyes may also be a source of infection.1 Recent research reported that the COVID-19 virus could survive and remain viable on plastics for up to 72 hours, 4 hours on stainless steel and copper and up to 24 hours on cardboard. Since the food sector has complex processing and manufacturing processes with a series of operational steps, starting from food intake, receiving, preparation, production, processing, packaging, storage and delivery to market and customers. At each stage, food handlers are directly involved, there is a more likelihood of food handlers touching the food or food surfaces directly. In this case, food workers are not following proper food safety control and protective actions, e.g., hand washings, cleaning and disinfection, sanitization, and social distancing. If not vaccinated, it can be a possible source of omicron transmission. To prevent the potential transmission of emerging Omicron SARS-COV-2 Variant of Concern, the food sector should ensure compliance with food safety control measures and prerequisites to safe and protect food workers from omicron variants to mitigate the risks of transmission of the virus by adopting good hygienic practices (GHPs), good manufacturing practices (GMPs), appropriate cleaning and disinfection by approved chemicals and sanitizers to endure the production and consistent stream of safe food. Since all the food workers may well be aware of the precaution’s measures, it is still needed to refresh their information. The staff working in food premises should be provided with frequent refresher training, proper personal protective equipment (PPEs), and written instructions on how to contain the transmission of Omicron and COVID-19 variants.2 One of the most critical steps to restrict the spread and transmission of the COVID-19 during food service processes is to wash and sanitize frequently. Frequent hand washing should be obligatory for Food workers directly involved in food production and preparation activities. The staff should avoid touching the food contact surfaces of tables, utensils, small wares, cutting boards and knives and surfaces of food menu, kiosks, dispensers, door handles, freezers and cooler handles, tablets, computers and equipment controller surfaces, buttons, and touchpads. There is a possibility that the virus can transfer from unwashed hands to other cleaned and sanitized surfaces during food production, preparations, cooking, storage, serving to customers and then moving to other food staff and eventually to customers. Frequent disinfection and sanitization with approved sanitizer to reduce the microorganism’s loads to a safe level determined by food safety authorities and public health codes are crucial to mitigating the risk of virus transmission. Social distancing to keep a space of at least 2 meters during operation hours at food premises to limit the close staff contacts inside food preparation and production areas is critically important to limit the spread.2 It is also recommended by CDC and other food safety authorities. The staff Should avoid unnecessary gatherings and crowds during shift changes, breaks and staff training. The food premises should optim ze the number of food workers to occupy maximum capacity at food premises and ensure fewer food workers are available than normal staff to a smaller amount of COVID-19 transmission risks.3,4 The food facilities should also provide appropriate personnel protective equipments (PPEs) for staff while receiving incoming materials and during deliveries, which can enhance the staff protection from the virus. Finally, the food amenities should look for staff health and monitor the visitors, suppliers, and contractors to recognize any sick person, maximize protection, and report to related health authorities if someone's symptoms are identical to emerging COVID-19 omicron variant concern. [ FROM AUTHOR] Copyright of Journal of Pure & Applied Microbiology is the property of Dr. M. N. Khan and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

13.
Trends Analyt Chem ; 155: 116585, 2022 Oct.
Article in English | MEDLINE | ID: covidwho-1730133

ABSTRACT

Wastewater-Based Epidemiology (WBE) is a novel community-wide monitoring tool that provides comprehensive real-time data of the public and environmental health status and can contribute to public health interventions, including those related to infectious disease outbreaks (e.g., the ongoing COVID-19 pandemic). Nonetheless, municipalities without centralized laboratories are likely still not able to process WBE samples. Biosensors are a potentially cost-effective solution to monitor the development of diseases through WBE to prevent local outbreaks. This review discusses the economic and technical feasibility of eighteen recently developed biosensors for the detection and monitoring of infectious disease agents in wastewater, prospecting the prevention of future pandemics.

14.
J Drug Deliv Sci Technol ; 70: 103219, 2022 Apr.
Article in English | MEDLINE | ID: covidwho-1720287

ABSTRACT

Respiratory diseases are leading causes of death and disability in developing and developed countries. The burden of acute and chronic respiratory diseases has been rising throughout the world and represents a major problem in the public health system. Acute respiratory diseases include pneumonia, influenza, SARS-CoV-2 and MERS viral infections; while chronic obstructive pulmonary disease (COPD), asthma and, occupational lung diseases (asbestosis, pneumoconiosis) and other parenchymal lung diseases namely lung cancer and tuberculosis are examples of chronic respiratory diseases. Importantly, chronic respiratory diseases are not curable and treatments for acute pathologies are particularly challenging. For that reason, the integration of nanotechnology to existing drugs or for the development of new treatments potentially benefits the therapeutic goals by making drugs more effective and exhibit fewer undesirable side effects to treat these conditions. Moreover, the integration of different nanostructures enables improvement of drug bioavailability, transport and delivery compared to stand-alone drugs in traditional respiratory therapy. Notably, there has been great progress in translating nanotechnology-based cancer therapies and diagnostics into the clinic; however, researchers in recent years have focused on the application of nanostructures in other relevant pulmonary diseases as revealed in our database search. Furthermore, polymeric nanoparticles and micelles are the most studied nanostructures in a wide range of diseases; however, liposomal nanostructures are recognized to be some of the most successful commercial drug delivery systems. In conclusion, this review presents an overview of the recent and relevant research in drug delivery systems for the treatment of different pulmonary diseases and outlines the trends, limitations, importance and application of nanomedicine technology in treatment and diagnosis and future work in this field.

16.
Case Studies in Chemical and Environmental Engineering ; 4:100127, 2021.
Article in English | ScienceDirect | ID: covidwho-1377690

ABSTRACT

During the last decades, the growth of concern towards different pollutants has been increasing due to population activities in large cities and the great need for food production by the agri-food industry. The effects observed in specific locations have shown the impact over the environment in air, soil and water. Specifically, the current pandemic of COVID-19 has brought into the picture the intensive use of different medical substances to treat the disease and population intensive misuse. In particular, the use of antibiotics has increased during the last 20 years with few regulations regarding their excessive use and the disposal of their residues from different sources. Within this review, an overview of sources of antibiotics to aquatic environments was done along with its impact to the environment and trophic chain, and negative effects of human health due prolonged exposure which endanger the environment, population health, water, and food sustainability. The revision indicates the differences between sources and its potential danger due toxicity, and accumulation that prevents water sustainability in the long run.

17.
Int Immunopharmacol ; 99: 108050, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1347667

ABSTRACT

The COVID-19 pandemic challenges have been only partially addressed so far. The pathogenicity of SARS-CoV-2 is considered the combination of severe and high infectivity. Herdimmunity is attained when a critical proportion of the population is immune, providing the virus with fewer chances to spread locally. To overcome the rising tide of the COVID-19 pandemic, efficacious and safe vaccines providing defensive and long-lasting immunity responses are urgently needed.Vaccines that induce virus-neutralizing antibodies with great affinity can optimally fight against infection. Worldwide, over 120 novel vaccine candidates, including live-attenuated, inactivated, viral-vectored nonreplicating and replicating, peptide- and protein-based, and nucleic acid-based approaches are in the process of preclinical and clinical trials (phase 1-4). In addition to comprehensive safety assessments and immune responses, precise clinical management is also important for trials of vaccines. The recent emergence of different variants of SARS-CoV-2 is becoming a new threat for the world and a challenge for scientists to introduce the most influential vaccine against COVID-19. The possibility of natural and vaccine-induced immunity in variants finds it necessary to establish next-generation vaccines, which generate general neutralization against existing and future variants. Here, we summarize the cellular and humoral responses of SARS-CoV-2, current progress in vaccination development, the antibody titer response of available phase 4 vaccinations in vaccinated populations of different countries worldwide, and the success and challenges ahead of vaccine development.


Subject(s)
COVID-19 Vaccines/therapeutic use , COVID-19/prevention & control , Pandemics/prevention & control , COVID-19 Serological Testing , Humans , Immunity/immunology , SARS-CoV-2 , Vaccination
18.
American Journal of Respiratory and Critical Care Medicine ; 203(9), 2021.
Article in English | EMBASE | ID: covidwho-1277318

ABSTRACT

Rationale: While COVID-19 can result in multi-organ failure, the primary site of involvement is the lungs. There have been concerns throughout the pandemic about patients with underlying chronic lung diseases like Chronic Obstructive Pulmonary Disease (COPD) and asthma. However, there is paucity of data in these patients, especially from a rural setting. Methods: We conducted a retrospective study of 301 patient 18 years and older, admitted with symptomatic COVID-19 infection to 8 Vidant health system hospitals in Eastern North Carolina (ENC) from March 1,2020 to July 15,2020. Primary objective was to assess prevalence of asthma and COPD in patients hospitalized with symptomatic COVID-19. Secondary objectives were to compare need for ICU admission, mechanical ventilation (MV), MV duration, ICU length of stay (LOS), hospital LOS, and mortality between patients with and without COPD and asthma, and between obese and non-obese asthmatics. Nonparametric tests and binary regression analyses were performed as appropriate to analyze differences between clinical covariates of interest. Results: Average age of the sample was 63.5 years (±17.1 years). N= 158 (52.5%) of the patients were females. Majority of the patients were African Americans (n=196, 65%). Most common comorbidities included hypertension (n=230, 76%), diabetes (n=155, 51%) and obesity (n=158, 52%). Prevalence of asthma and COPD was 16% (n=47) and 12% (n=36), respectively. More patients with COPD were admitted to the ICU(n=20, 56%) compared to asthma(n=22, 47%) and those with neither condition(n=85, 38%). Compared to patients with neither condition, COPD was significantly associated with increased risk of ICU admission(OR=2.4,p=0.03,CI=1.1-4.99) whereas asthma was not(OR=1.5,p=0.24,CI=0.77-2.9). There were no significant differences in rates of intubation, MV duration, ICU or hospital LOS, or in-hospital survival(Table 1). Based on a limited sample size, obesity in asthma was not significantly associated with increased risk of ICU admission, intubation, prolonged MV, prolonged hospital or ICU LOS, or mortality (n=33 obese asthmatics, n=14 non-obese asthmatics). Increased risk of mortality was significantly associated with older age (OR=1.04, p=0.003). Kaplan-Meier analyses of survival did not reveal a decrease in in-hospital survival in patients with COPD and asthma. Conclusion: Our study shows that asthma and COPD are among the less common comorbidities of COVID-19. Compared to some other studies, our study does not show worse outcomes for COPD or asthma. Larger cohorts are required to establish predictors of outcomes in these patient populations.

19.
J Infect Public Health ; 14(3): 331-346, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1002799

ABSTRACT

The recent emergence of novel coronavirus disease (COVID-19) triggered by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has resulted in substantial mortality worldwide. Presently, there is no approved treatment for COVID-19. Consequently, the clinical, scientific, and regulatory authorities have joint efforts to reduce the severe impact of COVID-19. To date, there is minimal arsenal with no definite curative drugs, licensed-vaccines, or therapeutic conducts to combat the COVID-19 infections. Keeping in view the threats of this pandemic, various global organizations, physicians, researchers, and scientists, are trying to recognize the epidemiological characteristics and pathogenic mechanisms of COVID-19 to discover potential treatment regimens, vaccines, and therapeutic modes for future anticipation. Herein, we summarize a contemporary overview of curative invasions and vaccines for COVID-19 based on the earlier information and considerate of similar earlier RNA coronaviruses. The information reviewed here establishes a paramount intellectual basis to promote ongoing research to develop vaccines and curative agents. Thus, this review suggests the furthermost accessible frontiers in the vaccine development to tackle or combat the COVID-19/SARS-CoV-2.


Subject(s)
COVID-19 Drug Treatment , COVID-19/prevention & control , Risk Management , Antiviral Agents/therapeutic use , COVID-19 Vaccines , Humans , Male , Multicenter Studies as Topic , Pandemics , Randomized Controlled Trials as Topic , SARS-CoV-2
20.
Case Studies in Chemical and Environmental Engineering ; : 100074, 2020.
Article in English | ScienceDirect | ID: covidwho-987426

ABSTRACT

The COVID-19 pandemic has been one of the biggest challenges worldwide. The psychological disorders associated with the pandemic causing depression, insomnia, post-traumatic stress disorder (PTSD) and anxiety reduce emotional stability. Different antidepressant drugs with several mechanisms of action are used with a prescription. The excretion of the compounds and their metabolites reach municipal wastewaters and enter sewage treatment plants with a low rate of remotion of pharmaceutical compounds and the releasing on the environment. Several effects on aquatic species exposed to antidepressants have been reported as the impact in gene transcription, reproduction cycles, predator defense, and motility. The aim of this work is to resume the common antidepressants detected in wastewater around the world and show the increment of its use during SARS-CoV-2 crisis.

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